Impact of subclinical hypothyroidism treatment in systolic and diastolic cardiac function

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Impact of subclinical hypothyroidism treatment in systolic and diastolic cardiac function.

OBJECTIVE To evaluate the effects of levothyroxine (L-T4) replacement in echocardiographic parameters of middle-aged women with subclinical hypothyroidism (SH). SUBJECTS AND METHODS This was a randomized, double-blind, placebo-controlled study. Echocardiographic evaluation was carried out at baseline and one year after restoration of euthyroidism. Thirty-three women with SH were assigned to o...

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Effect of levothyroxine on cardiac function in children with subclinical hypothyroidism: A quasi-experimental study

Background: Because of the importance of thyroid function and its effect on different organs, such as the heart, this study was aimed to evaluate the effect of levothyroxine on cardiac function in children with subclinical hypothyroidism. Methods: This quasi-experimental study was performed on children aged 4-12 years old with diagnosis of subclinical hypothyroidism in Amirkola Children's Hosp...

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Cardiac systolic and diastolic function during whole body heat stress.

During a whole body heat stress, stroke volume is either maintained or slightly elevated despite reduced ventricular filling pressures and central blood volume, suggestive of improved cardiac diastolic and/or systolic function. Heat stress improves cardiac systolic and diastolic function in patients with congestive heart failure, although it remains unknown whether similar responses occur in he...

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LEFT VENTRICULAR DIASTOLIC ABNORMALITIES IN β-THALASSEMIA MAJOR WITH NORMAL SYSTOLIC FUNCTION

In order to identify left ventricular diastolic function in patients with betathalassemia major and normal systolic function by noninvasive M-mode and Doppler echocardiography, an analytic study was designed in a university hospital in Sari. We have studied 44 patients (23 men and 21 women), mean age 15.48±2.16 (range 12 to 20) and 43 age and sex matched control subjects. Peak flow velocit...

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Subclinical hypothyroidism: Identification and treatment in pregnancy

Thyroid disorders are the commonly detected endocrinopathies during pregnancy. It seems that prevalence of hypothyroidism is more in Asian countries compared with the West [1,2]. The majority of cases of hypothyroidism are considered to be subclinical type. In west, the prevalence of hypothyroidism is estimated to be 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively [2-4]....

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ژورنال

عنوان ژورنال: Arquivos Brasileiros de Endocrinologia & Metabologia

سال: 2011

ISSN: 0004-2730

DOI: 10.1590/s0004-27302011000700005